Book Detail:
Author: Heide Schatten
Publisher: Springer
ISBN: 1493929046
Size: 80.42 MB
Format: PDF, ePub
Release Date: 2015-08-21
Category: Science
Language: en
View: 889
Status: Available

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Book Description
Download PDF The Cytoskeleton In Health And Disease eBook. You can read online on your kindle, Android, iPhone, iPad. This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.

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Book Detail:
Author: Manfred Schliwa
Publisher: Springer Science & Business Media
ISBN: 3709176670
Size: 57.35 MB
Format: PDF, ePub
Release Date: 2012-12-06
Category: Science
Language: en
View: 2971
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. The term cytoskeleton has become firmly established in today's scientific vocabulary. Indeed, it is difficult to believe that only ten years ago, it was virtually non-existent. Since then, the modern field of research on the structural organization of the cytoplasm has turned into one of the most productive and rapidly expanding research areas in Cell Biology today. Considerable progress has been made towards the identification of the various structural components of the cytoskeleton and their interactions with one another and with membranes. The first attempts to understand, in molecular terms, complex cellular processes such as shape changes, locomotion, division, and organelle movements have been made. And it is now apparent that the cytoskeleton has impact on other biological processes such as the control of gene expression, protein synthesis, cell cycle regulation, and development. This monograph outlines the basic properties of the major components of the polymeric filament networks and their interactions and associations. Wherever possible, emphasis is placed on more recent references. Any attempt to cover a research field this complex in an introductory mono graph is, by necessity, fragmentary, and oversights or omissions are inevitable. I wish to apologize in advance to all those colleagues who feel that their work is not adequately represented.

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Book Detail:
Author:
Publisher: Elsevier
ISBN: 9780080469393
Size: 22.56 MB
Format: PDF, ePub, Docs
Release Date: 2011-09-02
Category: Science
Language: en
View: 4603
Status: Available

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Book Description
Download PDF Aspects Of The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. This volume provides an overview of the cytoskeleton particularly on the fundamental role the cytoskeleton plays in the regulation of cell structure and function. This book represents new trends in cytoskeletal research that go beyond the traditional approach of identifying new proteins in the cytoskeleton, but actually define how these proteins interact with signaling pathways. While the major emphasis in this volume remains on the microfilament structure, some discussion has been included in this volume to illustrate the similarities and differences between the three cytoskeletal elements namely the actin microfilament, the intermediate filaments and the microtubules.

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Book Detail:
Author: Jerry Shay
Publisher: Springer
ISBN: 9781468445947
Size: 53.23 MB
Format: PDF, ePub, Mobi
Release Date: 2013-10-21
Category: Medical
Language: en
View: 3748
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. The preceding volumes of Cell and Muscle Motility have focused on various aspects of motile systems in both muscle and non muscle cells. These essays have been critical reviews on topics of current interest and, hopefully, have provided a base from which future investigations may develop. During the past decade, however, much attention in the fields of biochemistry and cell biology has focused on motile systems in non muscle cells. Our current under standing of the three-dimensional organization of the cytoplasm involve three major fibrous proteins which are collectively known as the cytoskeletal system. These polymorphic cytoskeletal proteins are microtubules (25-nm diameter), microfilaments (6-nm diameter), and intermediate filaments (lO-nm diame ter). Microtubules consist of tubulin and several well-characterized micro tubule associated proteins (MAPs) including MAP , MAP , tau, and others. l 2 Microfilaments consist of actin and associate with actin-binding proteins in cluding a-actinin, filamin, myosin, tropomyosin, vinculin, and others. Inter mediate filaments (lO-nm filaments) consist of at least five different tissue specific classes, including desmin or skeletin (muscle), prekeratin (epithelial), vimentin (mesenchymal), neurofilament (nerve), and glial acidic fibrillary protein (astrocytes). These major fibrous proteins apparently interact with each other as well as other cytoplasmic components and appear to be inti mately associated with such biological processes as cell shape changes, growth, motility, secretion, cell division, and uptake of materials from the exterior of the cell.

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Book Detail:
Author: Kermit L. Carraway
Publisher: Oxford University Press, USA
ISBN:
Size: 50.63 MB
Format: PDF, ePub, Mobi
Release Date: 1992
Category: Cytology
Language: en
View: 7628
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. Cytoskeletal research has undergone rapid progress in recent years and is currently an area of research activity. This book provides a wealth of methods and expert advice for investigating the cytoskeletal elements of eukaryotic cells. It focuses on the dynamic and functional aspects of the three major systems of the cytoskeleton--microfilaments, intermediate filaments and microtubules, and their interactions with their associate proteins. Detailed experimental protocols for state-of-the-art techniques are given throughout, and emphasis is placed on recent advances in areas such as video microscopy, molecular biology, immunological analysis, and microchemistry of proteins. This comprehensive volume will be useful to both experienced and novice researchers who wish to apply the technologies available for the study of these important components of eukaryotic cell structure.

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Book Detail:
Author: J.W. Shay
Publisher: Springer Science & Business Media
ISBN: 1461321514
Size: 40.10 MB
Format: PDF, ePub, Docs
Release Date: 2013-11-11
Category: Science
Language: en
View: 7318
Status: Available

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Book Description
Download PDF Cell And Molecular Biology Of The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad.

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Book Detail:
Author: Terence M. Preston
Publisher: Blackie Academic and Professional
ISBN:
Size: 64.54 MB
Format: PDF, Docs
Release Date: 1990
Category: Cells
Language: en
View: 3516
Status: Available

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Book Description
Download PDF The Cytoskeleton And Cell Motility eBook. You can read online on your kindle, Android, iPhone, iPad.

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Book Detail:
Author: Thomas W. Clarkson
Publisher: Springer Science & Business Media
ISBN: 1461321611
Size: 68.30 MB
Format: PDF, Docs
Release Date: 2012-12-06
Category: Science
Language: en
View: 3525
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. This book is based on reviews and research presentations given at the 16th Rochester International Conference on Environmental Toxicity, entitled liThe Cytoskeleton: A Target for Toxic Agents," held on June 4, 5 and 6 in 1984. The conference provided an in-depth discussion of the effects a~d mechanism of action of some toxic agents on the cytoskeleton. Mamma"lian and other eukaryotic cells contain protein networks within the cytoplasm comprised of microfilaments, intermediate Hlaments and microtubules. These components of the cytoskeleton playa key role in cell shape, motility, intracellular organization and transport, and cell division. Furthermore, the cytoskeleton, via associations with the cell membrane, appears to function in intracellular communication and cellular responses to membrane events. Because of the complex functional roles of the cytoskeleton which vary with cell type, degree of differentiation, and cell cycle, its disruption may result in a variety of cellular changes. This expanding field in cell biology has already attracted the interest of toxicologists and environmental health scientists as a potentially fruitful area of research. Indeed, there is mounting evidence that certain toxic and chemotherapeutic compounds, as well as physical agents such as radiation and hydrostatic pressure, disrupt the normal structure and function of the cytoskeleton. This may be an important step in the overall expression of their action. It was, therefore, an opportune time to hold a conference to encourage the development of this area of toxicology and to suggest directions for future research.

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Book Detail:
Author:
Publisher: Academic Press
ISBN: 9780080859224
Size: 21.68 MB
Format: PDF, Docs
Release Date: 1982-08-04
Category: Science
Language: en
View: 1210
Status: Available

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Book Description
Download PDF The Cytoskeleton Part A eBook. You can read online on your kindle, Android, iPhone, iPad. The Cytoskeleton, Part A

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Book Detail:
Author: Thomas Dean Pollard
Publisher:
ISBN: 9781621820161
Size: 13.25 MB
Format: PDF, Kindle
Release Date: 2017
Category: Cell membranes
Language: en
View: 6163
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. The cytoskeleton is the intracellular filament system that controls the morphology of a cell, allows it to move, and provides trafficking routes for intracellular transport. It comprises three major filament systems-actin, microtubules, and intermediate filaments-along with a host of adaptors, regulators, molecular motors, and additional structural proteins. This textbook presents a comprehensive and up-to-date view of the cytoskeleton, cataloguing its many different components and explaining how they are functionally integrated in different cellular processes. It starts by laying out the basic molecular hardware, before describing in detail how these components are assembled in cells and linked to neighboring cells and the extracellular matrix to maintain tissue architecture. It then surveys the roles of the cytoskeleton in processes such as intracellular transport, cell motility, signal transduction, and cell division. The book is thus essential reading for students learning about intracellular structure. It also represents a vital reference for all cell and developmental biologists working in this field.

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Book Detail:
Author: A. B. Fulton
Publisher: Alice Fulton
ISBN: 9780412255106
Size: 22.40 MB
Format: PDF, ePub, Mobi
Release Date: 1984-09-27
Category: Juvenile Nonfiction
Language: en
View: 7730
Status: Available

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Book Description
Download PDF The Cytoskeleton Cellular Architecture And Choreography eBook. You can read online on your kindle, Android, iPhone, iPad. The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably con cerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a background knowledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with in standard introductory text books or are not dealt with in sufficient detail to enable the student to go on from them to read scholarly reviews with profit. This series of books is designed to satisfy this need. The authors have been asked to produce a brief outline of their subject assuming that their readers will have read and remembered much of a standard introductory textbook of biology. This outline then sets out to provide by building on this basis, the conceptual framework within which modern research work is progressing and aims to give the reader an indication of the problems, both conceptual and practical, which must be overcome if progress is to be maintained.

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Book Detail:
Author: Diedrik Menzel
Publisher: CRC Press
ISBN: 9780849366796
Size: 19.61 MB
Format: PDF, Kindle
Release Date: 1992-03-04
Category: Science
Language: en
View: 7129
Status: Available

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Book Description
Download PDF The Cytoskeleton Of The Algae eBook. You can read online on your kindle, Android, iPhone, iPad. The Cytoskeleton of the Algae provides a comprehensive examination of the structural features of the cytoskeleton in phylogenetic branches of algae. The book also analyzes the possible functions of cytoskeletal components using structural, physiological, genetic, and molecular approaches. Many taxa are described in detail, mirroring the dramatic progress that has been made in recent years in this new research field. Many unique structural elements and motility phenomena are described for the first time, and other features common to all plant cells, such as cell polarity, cytoplasmic streaming, mitosis, cell wall deposition, and contractile events are analyzed using algae as experimental model systems. The Cytoskeleton of the Algae reflects the enormous impact that research on the algal cytoskeleton has on both phycology and plant cell biology, and it will serve as an excellent reference volume for researchers in this area.

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Book Detail:
Author: Jonathon Howard
Publisher: Sinauer
ISBN: 9780878933334
Size: 29.97 MB
Format: PDF, Kindle
Release Date: 2005-12-06
Category: Science
Language: en
View: 6539
Status: Available

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Book Description
Download PDF Mechanics Of Motor Proteins And The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.

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Book Detail:
Author:
Publisher: Academic Press
ISBN: 0123984807
Size: 60.18 MB
Format: PDF, ePub, Docs
Release Date: 2014-03-11
Category: Science
Language: en
View: 3783
Status: Available

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Book Description
Download PDF Reconstituting The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cytoskeletal structure, including such topics as rotational movement of formins studied by fluorescence polarization microscopy, in vitro assembly assays for bacterial actin filaments, and modulators of microtubule plus end growth. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cytoskeletal structure Contains chapters with such topics as reconstitution of organelle transport and assaying microtubule nucleation by gamma-tubulin ring complex.

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Book Detail:
Author: Vaidurya Pratap Sahi
Publisher: Springer Nature
ISBN: 3030335283
Size: 76.37 MB
Format: PDF
Release Date: 2019-11-30
Category: Science
Language: en
View: 5270
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. This book focuses on the plant cytoskeleton and its various cross-talks with other cellular components leading to its role in plant growth and development. It not only allows the geometric and signaling dimensions of cells, but is also very important in physiological processes. The book discusses the recent studies showing the role of actin and microtubule cytoskeleton interactions in cell-wall assembly and dynamics. The authors examine the role of both microtubules in the mechanics of plant cells, and actin filaments in the motility of chloroplasts. Based on recent advances in the study of the acto-myosin complex using high-resolution microscopy, they propose a new model for intracellular transport in plants. Exploring an almost-forgotten field of bioelectricity in the context of the cytoskeleton, the book highlights connections between the dynamic actin filaments and the bioelectricity of membranes and demonstrates that the plant cytoskeleton is involved in the distribution of plant hormones. Lastly, it addresses the role of endomembrane -cytoskeleton interactions to show the importance of the cytoskeleton in organelle morphogenesis and cellular functions. Studies in various plant models have shown how the actin filament and microtubules control and coordinate plant cell growth and development. This book summarizes the mechanisms underlying these functions.

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Book Detail:
Author: Michael Melkonian
Publisher: Springer Science & Business Media
ISBN: 3709167140
Size: 26.10 MB
Format: PDF, ePub
Release Date: 2012-12-06
Category: Science
Language: en
View: 1947
Status: Available

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Book Description
Download PDF The Cytoskeleton Of Flagellate And Ciliate Protists eBook. You can read online on your kindle, Android, iPhone, iPad. This is a new type of calculus book: Students who master this text will be well versed in calculus and, in addition, possess a useful working knowledge of how to use modern symbolic mathematics software systems for solving problems in calculus. This will equip them with the mathematical competence they need for science and engineering and the competitive workplace. MACSYMA is used as the software in which the example programs and calculations are given. However, by the experience gained in this book, the student will also be able to use any of the other major mathematical software systems, like for example AXIOM, MATHEMATICA, MAPLE, DERIVE or REDUCE, for doing calculus on computers.

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Book Detail:
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Size: 21.27 MB
Format: PDF
Release Date: 2004
Category: Cells
Language: en
View: 156
Status: Available

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Book Description
Download PDF Molecular Biology Of The Cell eBook. You can read online on your kindle, Android, iPhone, iPad.

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Book Detail:
Author: Thomas W. Clarkson
Publisher: Springer
ISBN: 9780306422058
Size: 31.24 MB
Format: PDF
Release Date: 1999-02-24
Category: Science
Language: en
View: 3268
Status: Available

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Book Description
Download PDF The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. This book is based on reviews and research presentations given at the 16th Rochester International Conference on Environmental Toxicity, entitled liThe Cytoskeleton: A Target for Toxic Agents," held on June 4, 5 and 6 in 1984. The conference provided an in-depth discussion of the effects a~d mechanism of action of some toxic agents on the cytoskeleton. Mamma"lian and other eukaryotic cells contain protein networks within the cytoplasm comprised of microfilaments, intermediate Hlaments and microtubules. These components of the cytoskeleton playa key role in cell shape, motility, intracellular organization and transport, and cell division. Furthermore, the cytoskeleton, via associations with the cell membrane, appears to function in intracellular communication and cellular responses to membrane events. Because of the complex functional roles of the cytoskeleton which vary with cell type, degree of differentiation, and cell cycle, its disruption may result in a variety of cellular changes. This expanding field in cell biology has already attracted the interest of toxicologists and environmental health scientists as a potentially fruitful area of research. Indeed, there is mounting evidence that certain toxic and chemotherapeutic compounds, as well as physical agents such as radiation and hydrostatic pressure, disrupt the normal structure and function of the cytoskeleton. This may be an important step in the overall expression of their action. It was, therefore, an opportune time to hold a conference to encourage the development of this area of toxicology and to suggest directions for future research.

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Book Detail:
Author: Kermit L. Carraway
Publisher: Springer Science & Business Media
ISBN: 3662129930
Size: 66.86 MB
Format: PDF, ePub, Mobi
Release Date: 2013-03-09
Category: Science
Language: en
View: 7646
Status: Available

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Book Description
Download PDF Signaling And The Cytoskeleton eBook. You can read online on your kindle, Android, iPhone, iPad. This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

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Book Detail:
Author: Ralph A. Nixon
Publisher: Springer Science & Business Media
ISBN: 1441967877
Size: 40.89 MB
Format: PDF, ePub, Docs
Release Date: 2011-02-04
Category: Medical
Language: en
View: 6238
Status: Available

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Book Description
Download PDF Cytoskeleton Of The Nervous System eBook. You can read online on your kindle, Android, iPhone, iPad. This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.

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